dual recognition hypothesis
- dual recognition hypothesis
-
An outmoded hypothesis that is known to be incorrect now that the structure of the
T-cell receptor is known. The proposal was that viral (and some chemical) antigens were recognized in association with histocompatibility antigens by separate receptors on the T-cell. The generation of
cytotoxic T-cells was by association with Class I
MHC antigens, of
T-helper cells by association with Class II
MHC antigens. See
altered self hypothesis.
Dictionary of molecular biology.
2004.
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